SMEDDS Transparent Technology: A Revolutionary Method for Enhancing the Solubility and Absorption of Cosmetic Ingredients

The Self-Microemulsifying Drug Delivery System (SMEDDS) is an advanced formulation technology aimed at improving the solubility, stability, and bioavailability of poorly water-soluble materials. This technology is not only widely used in the pharmaceutical field but also exhibits unique advantages in the cosmetics industry.

SMEDDS is primarily composed of three core components: the oil phase, surfactants, and cosurfactants. For ingredients in cosmetics with low solubility and limited absorption capacity, SMEDDS technology can transform them into a self-emulsifying system, significantly increasing their solubility in water and thus enhancing their absorption effect.

The benefits of adopting SMEDDS are evident:

1、Significant improvement in solubility and dissolution: By forming fine drug molecule droplets in the microemulsion, SMEDDS effectively dissolves water-insoluble materials, expanding the surface area available for absorption.

2、Significant improvement in bioavailability: The extremely small size of microemulsion droplets facilitates rapid and efficient absorption of the product into the skin, thereby increasing its concentration in the extracorporeal circulation, i.e., bioavailability.

Enhanced skin permeation: Specific components in SMEDDS can act as skin permeation enhancers, improving the skin permeation effect of other cosmetic ingredients by altering the physicochemical properties of the skin surface.

3、Optimized delivery of specific ingredients: For active ingredients with low solubility or stability, SMEDDS technology can encapsulate them within microemulsion droplets, improving their solubility and stability in cosmetic formulations.

4、Potential controlled-release capability: By adjusting the excipients and composition of the formulation, SMEDDS has the potential to achieve controlled or sustained release characteristics of the product.

SMEDDS transparent technology brings a new solution to the cosmetics industry, not only improving the solubility and absorption performance of poorly soluble ingredients but also providing new possibilities for the delivery and controlled release of specific ingredients. 

If you are interested in SMEDDS transparent technology, please contact Aosen, and Aosen will provide you with a series of services related to SMEDDS transparent technology.